Kidney (Renal) Cancer

Verified discoveries, trials, and approvals for this cancer type. Every story separates evidence strength, regulatory status, and guideline position.

Latest Discoveries

Trial Watch: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Evidence stage: Later-Stage HumanRegulatory status: Investigational
Cancer type
Kidney (Renal) Cancer
Published
August 14, 2026

ClinicalTrials.gov confirms that this Phase 3 study is registered and currently listed as Active Not Recruiting. This establishes the study's existence and registry-reported design/status, not a treatment benefit.

Primary source cited

Last reviewed

Major Advances

Clinical Trials

Important: Eligibility and enrollment are not guaranteed, and listing here is not a treatment recommendation. Talk to your care team.

Trial Watch: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Regulatory status: InvestigationalEvidence stage: Later-Stage Human
Cancer type
Kidney (Renal) Cancer
Trial identifier
NCT04736706
Trial phase
Phase 3
View trial details
Study design
Other / not applicable
Population
Participants age 18 Years and older with Carcinoma, Renal Cell who meet the study-specific registry eligibility criteria.
Last reviewed
2026-08-14

Regulatory status by jurisdiction

Unspecified jurisdiction

Status
Investigational
Last verified
2026-08-14

This record has no structured cancer-type scope on file yet — editorial review recommended before treating it as applicable to a specific cancer type.

Primary evidence supporting this story

Eligibility varies — review trial criteria.

Personalized neoantigen vaccine shows no cancer recurrence in small phase 1 kidney cancer trial

Regulatory status: InvestigationalEvidence stage: Early Human
Cancer type
Kidney (Renal) Cancer
Trial identifier
NCT02950766
View trial details
Study design
Non-randomized trial
Population
Adults with high-risk, fully surgically resected clear cell renal cell carcinoma (stage III or IV, no remaining visible cancer after surgery), given a personalized neoantigen vaccine with or without ipilimumab in the adjuvant (post-surgery, preventive) setting, in a phase 1, first-in-human trial.
Last reviewed
2026-08-13

Regulatory status by jurisdiction

Unspecified jurisdiction

Status
Investigational
Last verified
2026-08-13

This record has no structured cancer-type scope on file yet — editorial review recommended before treating it as applicable to a specific cancer type.

Primary evidence supporting this story

Eligibility varies — review trial criteria.

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Trusted resources: official cancer information

CancerDiscoveries summarizes verified records in its database. Absence of a listing here does not establish that a treatment lacks regulatory authorization or access.