18-gene urine test improves detection of higher-grade prostate cancer in validation studies
Evidence stage: Later-Stage Human
Across two validation cohorts, an 18-gene urine test (MPS2) substantially outperformed PSA alone (AUC 0.81–0.82 vs. 0.60) for detecting higher-grade prostate cancer, with modeled reductions in unnecessary biopsies, including in…
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