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FDA approves the first all-oral combination regimen for older adults with newly diagnosed acute myeloid leukemia

Evidence stage: Emerging ClinicalRegulatory status: FDA Approved
Cancer type
Leukemia
Published
August 13, 2026

In the single-arm Study ASTX727-07, an all-oral combination of decitabine/cedazuridine (Inqovi) plus venetoclax produced a complete remission rate of 41.6% (and a combined complete-remission-or-partial-hematologic-recovery rate of 52.5%) in older or…

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