Discover verified cancer discoveries

Search and filter stories that passed editorial review. Evidence strength, regulatory status, and guideline position are shown separately and are never inferred from one another.

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2 verified discoveries match your filters.

Trial Watch: A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator’s Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)

Evidence stage: Later-Stage HumanRegulatory status: Investigational
Cancer type
Head and Neck Cancer
Published
September 24, 2026

ClinicalTrials.gov confirms that this Phase 3 study is registered and currently listed as Active Not Recruiting. This establishes the study's existence and registry-reported design/status, not a treatment benefit.

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FDA approves perioperative pembrolizumab for head and neck cancer — the first approval for this cancer in 6 years

Evidence stage: High-Certainty EvidenceRegulatory status: FDA Approved
Cancer type
Head and Neck Cancer
Published
August 13, 2026

In the randomized, open-label, phase 3 KEYNOTE-689 trial, adding pembrolizumab before and after surgery to standard treatment significantly extended event-free survival in patients with resectable, locally advanced, PD-L1-positive head and…

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