Discover verified cancer discoveries

Search and filter stories that passed editorial review. Evidence strength, regulatory status, and guideline position are shown separately and are never inferred from one another.

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17 verified discoveries match your filters.

Trial Watch: A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Research type: Registered later-phase trialRegulatory status: Investigational
Cancer type
Leukemia, Lymphoma
Published
August 26, 2026

ClinicalTrials.gov confirms that this Phase 3 study is registered and currently listed as Recruiting. This establishes the study's existence and registry-reported design/status, not a treatment benefit.

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Trial Watch: A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)

Research type: Registered later-phase trialRegulatory status: Investigational
Cancer type
Leukemia, Lymphoma
Published
August 24, 2026

ClinicalTrials.gov confirms that this Phase 3 study is registered and currently listed as Recruiting. This establishes the study's existence and registry-reported design/status, not a treatment benefit.

Primary source cited

Last reviewed

FDA approves blinatumomab in the consolidation phase of B-cell precursor acute lymphoblastic leukemia, regardless of MRD status

Research type: High-Certainty EvidenceRegulatory status: FDA Approved
Cancer type
Leukemia
Published
August 13, 2026

In the randomized, phase 3 ECOG-ACRIN E1910 trial, adding blinatumomab to consolidation chemotherapy significantly extended overall survival compared with chemotherapy alone in adults with MRD-negative B-cell precursor ALL — the…

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FDA approves the first all-oral combination regimen for older adults with newly diagnosed acute myeloid leukemia

Research type: Emerging ClinicalRegulatory status: FDA Approved
Cancer type
Leukemia
Published
August 13, 2026

In the single-arm Study ASTX727-07, an all-oral combination of decitabine/cedazuridine (Inqovi) plus venetoclax produced a complete remission rate of 41.6% (and a combined complete-remission-or-partial-hematologic-recovery rate of 52.5%) in older or…

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FDA grants traditional approval to pirtobrutinib for BTK-inhibitor-pretreated CLL/SLL

Research type: Later-stage studies in peopleRegulatory status: FDA Approved
Cancer type
Leukemia
Published
August 13, 2026

In the randomized, phase 3 BRUIN-CLL-321 trial, pirtobrutinib -- the first and only non-covalent (reversible) BTK inhibitor -- significantly extended progression-free survival compared with standard chemoimmunotherapy options in patients with…

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