Discover verified cancer discoveries

Search and filter stories that passed editorial review. Evidence strength, regulatory status, and guideline position are shown separately and are never inferred from one another.

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2 verified discoveries match your filters.

Trial Watch: A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)

Evidence stage: Later-Stage HumanRegulatory status: Investigational
Cancer type
Liver Cancer
Published
September 22, 2026

ClinicalTrials.gov confirms that this Phase 3 study is registered and currently listed as Active Not Recruiting. This establishes the study's existence and registry-reported design/status, not a treatment benefit.

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Adding lenvatinib and pembrolizumab to TACE improves progression-free survival in liver cancer, but the trial’s overall-survival goal was not met

Evidence stage: Later-Stage HumanRegulatory status: Investigational
Cancer type
Liver Cancer
Published
August 13, 2026

In the randomized, double-blind, phase 3 LEAP-012 trial, adding lenvatinib and pembrolizumab to TACE significantly extended progression-free survival compared with TACE alone (14.6 months versus 10.0 months) in patients with…

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Last reviewed