Our Mission: Highlighting Innovations by showcasing breakthroughs in cancer research, including diagnostic tools, therapies, and preventive measures.

Breast, Global Trends, mRNA & RNA-Based Therapies

Breast cancer breakthrough: Groundbreaking daily tablet could soon be made available on NHS

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A groundbreaking development in breast cancer treatment has emerged with the approval of elacestrant, a once-daily oral medication, by the National Institute for Health and Care Excellence (NICE) for use within the National Health Service (NHS) in England. This decision marks a significant policy reversal, as the drug was initially rejected in October due to uncertainties in the evidence. Elacestrant specifically targets advanced breast cancers that have developed mutations in the oestrogen receptor gene (ESR1), a common occurrence in up to half of advanced cases undergoing hormone therapy. These ESR1 mutations often render standard treatments ineffective, leading to disease progression. Clinical trials have demonstrated that elacestrant can delay disease progression by up to six months compared to existing therapies, offering renewed hope to over 1,100 women annually who are eligible for this treatment.

Elacestrant functions by binding to and degrading oestrogen receptors, thereby inhibiting the hormone’s ability to promote cancer cell growth and proliferation. This mechanism is particularly beneficial for patients whose cancers have become resistant to prior hormone therapies. To determine eligibility for elacestrant, patients will undergo genetic testing to identify the presence of ESR1 mutations. The availability of this targeted therapy on the NHS signifies a substantial advancement in personalized cancer care, aiming to extend survival and improve the quality of life for those affected by advanced breast cancer.

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Global Trends
ALONA MORANTA

This small berry may help fight cancer, diabetes, obesity

Scientists from UniversitŽ de MontrŽal have made an exciting discovery about the camu-camu berry, a fruit native to the Amazon rainforest. Already known for its health benefits, including protecting against obesity and diabetes, this small berry may also help in the fight against cancer.

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Cellular Research, Global Trends
ALONA MORANTA

This cancer drug may extend lifespan, study finds

Scientists from the University of Auckland have discovered that a cancer drug called alpelisib may help extend lifespanÑat least in mice. The researchers wanted to see whether this drug, which is currently used to treat certain cancers, could also slow down aging.

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Cellular Research, CRISPR & Gene Editing, mRNA & RNA-Based Therapies, Global Trends
ALONA MORANTA

TAU researchers use CRISPR to shrink cancer cells – study

Researchers at Tel Aviv University (TAU) successfully utilized CRISPR, a gene-editing technology, to remove a single gene from cancer cells in head and neck tumors. The study, conducted in animal models, resulted in the elimination of 50% of the tumors. The findings were published in the journal Advanced Science.

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