A recent study conducted by the UCLA Health Jonsson Comprehensive Cancer Center indicates that dietary modifications may decelerate the progression of prostate cancer in men opting for active surveillance. Published in the Journal of Clinical Oncology, the research focused on a diet low in omega-6 fats and high in omega-3 fats, supplemented with fish oil. Participants adhering to this regimen experienced a 15% reduction in the Ki-67 index—a marker indicating cancer cell proliferation—while the control group observed a 24% increase. These findings suggest that such dietary adjustments could potentially delay or even prevent the necessity for more aggressive treatments.
The study, known as CAPFISH-3, involved 100 men diagnosed with low-risk or favorable intermediate-risk prostate cancer. Those in the dietary intervention group received personalized counseling to reduce intake of omega-6-rich foods, such as processed snacks and fried items, replacing them with healthier alternatives like olive oil and vinegar for salads. Additionally, participants increased their omega-3 intake through fish oil supplements. While the Ki-67 index results were promising, no significant differences were observed in other cancer progression markers, such as the Gleason grade. This underscores the need for further research to fully understand the long-term benefits of balancing omega-3 and omega-6 fatty acids in managing prostate cancer. Click for More Details
