Discover verified cancer discoveries

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53 verified discoveries match your filters.

FDA approves inavolisib combination for PIK3CA-mutated, endocrine-resistant HR-positive breast cancer

Evidence stage: Later-Stage HumanRegulatory status: FDA Approved
Cancer type
Breast Cancer
Published
August 13, 2026

In the randomized, double-blind, placebo-controlled INAVO120 trial, adding inavolisib to palbociclib and fulvestrant significantly delayed disease progression compared with palbociclib and fulvestrant alone, in a PIK3CA-mutated, endocrine-resistant, first-line metastatic breast…

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FDA approves vorasidenib for IDH1/IDH2-mutant grade 2 glioma

Evidence stage: Later-Stage HumanRegulatory status: FDA Approved
Cancer type
Brain / CNS Cancer
Published
August 13, 2026

In the randomized, double-blind, placebo-controlled INDIGO trial, vorasidenib significantly delayed disease progression (by blinded independent review) and delayed the time to the next anticancer intervention, compared with placebo, in a…

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