Melatonin’s Anti-Cancer Potential; Prenatal PFAS and Cancer; Anti-Viral Gel for HPV

News, features, and commentary about cancer-related issues
Novel Drug Shrinks 73% of HER2-Mutant Lung Cancers

All were partial responses to antibody-drug conjugate in Chinese trial
Add-On Cemiplimab Shows Promise as First-Line Treatment for Penile Cancer

PD1 inhibitor plus chemo boosts outcomes in locally advanced or metastatic disease
Metastasis-Directed Therapy for Prostate Cancer a Clear Winner in Meta-Analysis

PFS more than doubled with standard of care plus MDT, but practice continues to evolve
Blood Test for Early Pancreatic Cancer Shows Promise

The blood test achieved high accuracy, with 98% specificity and 73% sensitivity for detecting pancreatic cancer.
Implant Shows Promise for Tumor-Specific Treatment in Prostate Cancer

Study shows feasibility of simultaneous delivery of multiple drugs, heterogeneous tumor response
FDA Expands Enhertu Approval to HER2-Ultralow Breast Cancer

T-DXd approved in metastatic HR-positive, HER2-low/ultralow disease following endocrine therapy
Immunotherapy-TACE Regimen Boosts PFS in Unresectable Liver Cancer

Add-on camrelizumab-rivoceranib also trended toward better OS in CARES-005
High Success Rate With Conversion Therapy for Unresectable Gastroesophageal Cancer

Three-fourths of patients had clear margins after surgery
Neoadjuvant Chemoradiation Plus Immunotherapy Boosts Responses in Esophageal Cancer

Phase III trial suggests regimen ‘has the potential to become the new standard of care’
Anti-TIGIT Shows Promise in Unresectable Liver Cancer

Early-stage study showed improved response rates and survival when added to standard of care
Use of Supplement for Glaucoma May Come With Liver Toxicity, Experts Warn

Specialists are ‘quite concerned’ about nicotinamide’s risk of hepatotoxicity, says expert