Glioblastoma treatment strategy reprograms cancer cells, halting tumor growth
UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.
Innovative CT scan technique could improve prognosis and treatments for head and neck cancers
Cancers occurring in the mouth, nose, and throat are on the rise in the U.S., especially in younger people. About 60,000 new cases are diagnosed every year, with one in five cases occurring in people younger than 55, according to the American Cancer Society. A new study provides insights that may eventually help oncologists better predict how the disease will respond to certain therapies, leading to improved survival outcomes for patients.
New technique to measure circulating tumor DNA in metastatic cancer may improve surveillance and outcomes
In metastatic cancer surveillance, monitoring the actual concentrations of circulating tumor DNA (ctDNA) may be critical. Researchers showed that absolute ctDNA concentration thresholds can be defined to rule out or predict impending cancer progression.
Pancreatic cancer RNA vaccine shows durable T cell immunity
Memorial Sloan Kettering Cancer Center researchers have found RNA neoantigen vaccines that generate long-lived, functional CD8+ T cells in patients with pancreatic ductal adenocarcinoma (PDAC), potentially delaying disease recurrence.
Researchers advance non-invasive cancer detection methods
Researchers at Vilnius University have developed an effective approach to liquid biopsy that contributes to the field of non-invasive cancer detection methods, with significant implications for personalized medicine.
Combining protein therapy and focused ultrasound therapy can improve cancer treatment
Combining an existing small-molecule protein therapy called tumor necrosis factor related apoptosis-inducing ligand (TRAIL) with focused ultrasound (FUS) can significantly reduce tumor size and burden in prostate cancer models, according to a new study published in Advanced Science by researchers at Rice University and Vanderbilt University.
Packing lipid nanoparticles with tumor proteins to boost cancer vaccine potency
The concept of using vaccines to treat cancers has been around for several decades.
Dysfunctional B cells: A novel target for cancer immunotherapy and diagnostics
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood—known as the tertiary lymphoid structure—where they become frustratingly dysfunctional when in close contact with tumors.
Scientists identify feature of aggressive non-small cell lung cancer
In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent.
Scientists uncover method to halt key driver of prostate and other cancers
Melbourne-based scientists have, for the first time, discovered how to “switch off” a molecule which is one of the top culprits behind prostate cancer, and is also linked to lung and kidney cancers.
Scientists discover the ‘roadmap’ that aggressive cancer uses to spread
New research published in Nature Communications reveals how cancer cells are altered by their surroundings, enabling them to change their shape and break out of a tumor.
Urinary DNA methylation test shows some promise for noninvasive bladder cancer screening
Researchers led by the University of Ulsan College of Medicine, Korea, have checked the performance of a noninvasive urinary DNA methylation test for bladder cancer diagnosis.
