Researchers at Aston University have developed a novel treatment for osteosarcoma, the most prevalent form of bone cancer. This approach utilizes bioactive glass infused with gallium, a metal known for its toxicity to cancer cells. In laboratory experiments, this gallium-doped bioactive glass demonstrated the ability to kill up to 99% of osteosarcoma cells without harming healthy bone cells. The gallium ions enter the cancer cells through specific receptors that are overexpressed in these malignant cells, leading to their destruction while sparing normal tissue.
Beyond its cancer-fighting properties, the bioactive glass shows potential in promoting bone regeneration. The material can dissolve gradually, releasing compounds that stimulate the growth of new, healthy bone tissue. This dual functionality suggests that gallium-doped bioactive glass could serve as an effective post-surgical implant, eradicating residual cancer cells and facilitating bone healing. Such a treatment could reduce the likelihood of cancer recurrence and improve recovery outcomes for patients undergoing surgery for osteosarcoma. Click for More Details
