Treatment Innovations
Innovations in cancer treatment are transforming patient care by introducing more precise, effective, and less invasive therapies. Immunotherapy, including checkpoint inhibitors and CAR-T cell therapy, has revolutionized cancer care by harnessing the immune system to target and destroy cancer cells.
Combining protein therapy and focused ultrasound therapy can improve cancer treatment
Combining an existing small-molecule protein therapy called tumor necrosis factor related apoptosis-inducing ligand (TRAIL) with focused ultrasound (FUS) can significantly reduce tumor size and burden in prostate cancer models, according to a new study published in Advanced Science by researchers at Rice University and Vanderbilt University.
Packing lipid nanoparticles with tumor proteins to boost cancer vaccine potency
The concept of using vaccines to treat cancers has been around for several decades.
Scientists find the cause of stomach cancer growth and spread
Researchers have discovered that stomach cancer cells connect with nearby sensory nerves, forming electrical circuitsthat fuel tumor growth and help the cancer spread.
How to lower your risk of skin cancer
GRAND RAPIDS, Mich. (WOOD) — Skin cancer is the most common form of cancer worldwide, and an estimated 1 in 5 Americans develop it by age 70, the Skin Cancer Foundation says. Luckily, there are practical ways to lower your risk of getting it.
Dysfunctional B cells: A novel target for cancer immunotherapy and diagnostics
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood—known as the tertiary lymphoid structure—where they become frustratingly dysfunctional when in close contact with tumors.
Scientists identify feature of aggressive non-small cell lung cancer
In localized non-small cell lung cancer (NSCLC), a tumor’s ability to use carbon from glucose to feed the tricarboxylic acid (TCA) cycle predicts cancer spread beyond the lung, months to years before metastases are clinically apparent.
Self-assembling nanoplatform can boost cancer photoimmunotherapy effectiveness
Photoimmunotherapy is an innovative cancer treatment that combines phototherapy with immunotherapy to selectively target and destroy cancer cells.
Higher Calcium Intake Linked to Reduced Colorectal Cancer Risk
Finding was consistent across calcium sources and tumor sites
Quantum camera could help detect cancer as soon as it forms
The imminent development of quantum cameras promises to transform many sectors, starting with medicine.
Self-protecting nanoparticles can enhance colorectal cancer drug delivery
Colorectal cancer (CRC) is one of the most prevalent types of cancer and has a high mortality rate globally. Oral administration of anticancer drugs that pass through the gastrointestinal (GI) tract into the colorectum is a common strategy to deliver drugs in CRC treatment.
Talazoparib + Enzalutamide Tied to Improved Overall Survival in Metastatic Prostate Cancer
WEDNESDAY, Feb. 19, 2025 (HealthDay News) — For patients with metastatic castration-resistant prostate cancer (mCRPC) unselected for homologous recombination repair (HRR) gene alterations, talazoparib (TALA) + enzalutamide (ENZA) is associated with improved overall survival versus placebo + ENZA, according to a study presented at the American Society of Clinical Oncology annual Genitourinary Cancers Symposium, held from Feb. 13 to 15 in San Francisco.
Testosterone Recovery Linked to Overall Survival in High-Risk Prostate Cancer
TUESDAY, Feb. 18, 2025 (HealthDay News) — Serum testosterone (T) recovery to normal levels is associated with a significant improvement in overall survival in patients with high-risk prostate cancer receiving radiotherapy and long-term androgen deprivation therapy (ADT), according to a study presented at the American Society of Clinical Oncology annual Genitourinary Cancers Symposium, held from Feb. 13 to 15 in San Francisco.
Genetically altered mice shed light on skin cancer
Research in Asia and Europe has provided further insights into how disruption to communication between the gut and brain could have an effect on anxiety levels and diseases such as Alzheimer’s.
KN026-Docetaxel Combo Shows Efficacy, Safety in HER2+ Metastatic Breast Cancer
KN026, a HER2-directed bispecific antibody, plus docetaxel achieved long-term response with manageable safety as a first line of therapy for patients with recurrent/metastatic HER2-positive breast cancer, as demonstrated by phase 2 trial (NCT04165993) results published in Cancer Communications
NHS launches first-ever breast screening campaign to help detect thousands of cancers earlier
Thousands more breast cancers could be detected earlier in England next year in a major new NHS drive to support more women to attend potentially life-saving breast screening.
Support Throughout the Entire Cancer Journey
Dr. Sanft, who describes herself as a “very midwestern girl, through and through,” was raised in a mid-size town in Iowa and decided to become a doctor when she was quite young.
Uncovering inequalities in breast cancer immunotherapy access
The study examines trends in immunotherapy treatment for triple-negative breast cancer since the new therapies were approved.
New blood cancer drug has a 97% cure rate
Researchers at the University of Hong Kong’s LKS Faculty of Medicine (HKUMed) have developed an oral form of arsenic trioxide (Oral-ATO; ARSENOL) to treat acute promyelocytic leukemia (APL), a once-deadly type of blood cancer.
Scientists uncover method to halt key driver of prostate and other cancers
Melbourne-based scientists have, for the first time, discovered how to “switch off” a molecule which is one of the top culprits behind prostate cancer, and is also linked to lung and kidney cancers.
Cell Signalling (Oncology)
We study signal transduction in cells. We focus on the PI3K signalling molecules which are overactive in cancer and in overgrowth syndromes. We aim to understand PI3K action and use that for therapies
Antibody therapy shrinks immunotherapy-resistant lung cancer tumors in mice
An investigational therapy significantly shrank lung cancer tumors that are notoriously resistant to treatment by encouraging an attack from natural killer (NK) cells in an animal model, a study led by UT Southwestern Medical Center researchers shows.
Arcus Challenges Merck in Kidney Cancer with Early Data
Casdatifan’s progression-free survival benefits could help differentiate it from Merck’s Welireg in the kidney cancer arena, according to analysts at Truist Securities.
CAR T-cells enable record-breaking 18-year nerve cancer remission
CAR T-cells enable record-breaking 18-year nerve cancer remission
Comprehensive CT Scans May Help to Identify Atherosclerosis Among Patients With Lung Cancer
Several cardiovascular risk factors such as advanced age and smoking history may be prevalent among patients with lung cancer at the time of diagnosis and may increase their risk of future cardiovascular disease,
