Treatment Innovations
Innovations in cancer treatment are transforming patient care by introducing more precise, effective, and less invasive therapies. Immunotherapy, including checkpoint inhibitors and CAR-T cell therapy, has revolutionized cancer care by harnessing the immune system to target and destroy cancer cells.
Study finds stem-like T cells key to lasting immune response in cancer, chronic diseases
Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders—T cells—lose their ability to function effectively. Research, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and the Peter MacCallum Cancer Center (Peter Mac), have identified a rare type of immune cells, called stem-like T cells, that holds the key to maintaining powerful, long-term immune responses.
TROPION-Lung12 phase 3 trial initiated evaluating Datroway as part of adjuvant regimen for patients with early-stage NSCLC at high risk of relapse
he first patient has been dosed in the TROPION-Lung12 phase 3 trial evaluating the efficacy and safety of adjuvant Datroway (datopotamab deruxtecan) plus rilvegostomig or rilvegostomig monotherapy versus standard of care in patients with stage 1 adenocarcinoma non-small cell lung cancer (NSCLC) after complete surgical resection who are ctDNA-positive or have other high risk pathological features.
Wales and Northern Ireland work together on groundbreaking cancer innovation projects | Welsh Government
Five innovative projects across Wales and Northern Ireland have been awarded a share of £1 million to develop technology to reduce waiting times and improve outcomes for cancer patients.
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Accelerating Cancer Treatment with Precision Medicine & NGS
Asia accounts for nearly half of global cancer cases, making it a major health concern. Recognising the promise of precision oncology, governments across the region have initiated efforts to drive advancements in this space. Let’s take a closer look at the progress being made in precision oncology in the Asia Pacific region.
AI maps molecular interaction that could improve cancer research
A new study from Oregon Health & Science University has uncovered how small molecules within bacteria interact with proteins, revealing a network of molecular connections that could improve drug discovery and cancer research.
AI Tailors Cancer Treatment to Individual Patients
A novel AI tool from BIFOLD and partner institutions deciphers complex cancer interrelationships, enhancing personalized medicine and clinical decision-making.
Combined strategy can prevent pancreatic cancer drug resistance
Understanding the mechanisms of resistance to cancer treatments is necessary to find effective therapies at different stages of the disease. Scientists at UT Southwestern Medical Center studied the most frequent mutation in pancreatic ductal adenocarcinoma (PDAC), identified an escape route to a therapy in clinical trials, blocked it with another experimental compound and reduced tumors in mice.
Huntsman Cancer Institute leads the way with advanced robotic surgery technology
Huntsman Cancer Institute at the University of Utah (the U) proudly announces the addition of two da Vinci 5 robotic surgical systems.
Innovative Medicines
Patients with a wide range of life-threatening and debilitating illnesses today live in the hope tomorrow will bring a new medicine that will improve or even save their life. America’s biopharmaceutical research companies are researching and developing new medicines to meet unmet need and continuing research and development even after U.S. Food and Drug Administration (FDA) approval, all with the goal of improving patients’ health, quality of life, and saving lives.
New research unlocks key to long-lasting immune response in cancer and chronic diseases
Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders — T cells — lose their ability to function effectively. Researchers have identified a rare type of immune cells, called stem-like T cells, that holds the key to maintaining powerful, long-term immune responses.
New cutting-edge equipment advances surgical care at Rupert Hospital
Prince Rupert Regional Hospital has acquired new state-of-the-art equipment, significantly advancing surgical care for patients.
Royal Surrey staff celebrate radiotherapy treatment for 500th rectal cancer patient
The Royal Surrey NHS Foundation Trust celebrates a milestone, having successfully treated its 500th rectal cancer patient with radiotherapy.
Targeting MYCN and MDM2 offers new hope for cancer therapy
Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.
Biomarker predicts KRASG12C inhibitor success in lung cancer treatment
A new study from Moffitt Cancer Center could help doctors predict how well patients with a specific type of lung cancer will respond to new therapies. The research, published in Clinical Cancer Research, found that measuring the interaction between two proteins, RAS and RAF, could provide valuable insights into the effectiveness of treatments for patients with KRASG12C-mutant non-small cell lung cancer, a type of lung cancer known for being particularly difficult to treat.
Dwyane Wade Reveals He Had Part Of Kidney Removed As Result Of Cancerous Tumor
Former NBA star Dwyane Wade revealed on his podcast that he had to have part of his kidney removed as the result of a tumor.
How ‘Prehab’ and Rehab Can Change the Game for Lung Cancer Patients
Participating in a supervised exercise and education program prior to treatment may improve recovery and survival. ‘Prehabbing’ can also help make surgery viable for lung cancer patients who weren’t candidates before.
How scientists redesigned an effective cancer therapy to make it safer
University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage. If approved, the new drug may be tolerated by a broader range of leukemia patients and even be used to treat other cancers.
Restaurant critic Giles Coren reveals he has prostate cancer
Award-winning food and drink writer says he only asked for test thanks to Stephen Fry and Chris Hoy raising awareness
Moffitt Cancer Center Announces New Proton Therapy Treatment
Moffitt Cancer Center has introduced a new proton therapy treatment, offering advanced options for cancer patients.
Strutting Into Year 11 With Metastatic Breast Cancer
After living with metastatic breast cancer for 11 years, I reflect on my journey and plan to embrace the coming year with confidence and self-advocacy.
Early Palliative Care Improves EOL Comfort in Colorectal Cancer
Early palliative care reduces invasive interventions and enhances comfort at EOL for CRC patients, according to real-world study results.
Amarogentin suppresses cell proliferation and EMT process through inducing ferroptosis in colorectal cancer – BMC Gastroenterology
Background Colorectal cancer (CRC) is one common tumor with the high death rate, and badly affects the normal lives of CRC patients. Amarogentin (AG) has been found to exhibit regulatory roles and join into the progression of multiple diseases. However, the regulatory impacts and associated molecular mechanisms of AG in CRC progression keep unclear. Methods and results In this study, it was demonstrated that AG weakened CRC cell viability in a concentration- and time-dependent manner. In addition, AG accelerated cell apoptosis by triggering ferroptosis. The cell invasion and EMT process were restrained after AG treatment, but these impacts were reversed after Fer-1 addition. Moreover, it was uncovered that AG retarded Nrf2/HO-1/GPX4 activation. Additionally, AG modulated PTC cell viability and stimulated ferroptosis. At last, it was illustrated that AG suppressed tumor growth in vivo. Conclusion In conclusion, it was disclosed that AG suppressed cell proliferation and EMT process through inducing ferroptosis in CRC, and retarded Nrf2/HO-1/GPX4 activation. This discovery suggested that AG may be one effective drug for ameliorating CRC progression.
Gene discovery revolutionizes the detection and treatment of prostate cancer
A recent gene discovery has the potential to revolutionize how prostate cancer is detected and treated, offering new hope for patients.
Baptist MD Anderson to launch cellular therapy, stem cell program – The Ponte Vedra Recorder
As part of Baptist Health’s ongoing work to advance cancer care in Northeast Florida and Southeast Georgia, the health system is launching a Stem Cell Transplantation and Cellular Therapy Program …
